9H7G

Human Transthyretin in Complex with 1H-indole-3-carbonitrile

Summary for 9H7G

• Entry DOI: 10.2210/pdb9h7g/pdb
• Descriptor: Transthyretin, CALCIUM ION, 1~{H}-indole-3-carbonitrile, ... (4 entities in total)
• Functional Keywords: amyloidosis, retinol, thyroxine, rbp, transport protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 27919.19

Authors

Chen, W. (deposition date: 2024-10-27, release date: 2025-03-12)

• Primary citation: Chen, W.; Fragment-Based Drug Discovery for Transthyretin Kinetic Stabilisers Using a Novel Capillary Zone Electrophoresis Method; Biorxiv, 2025; DOI: 10.1101/2025.02.22.639275

Experimental method

X-RAY DIFFRACTION (1.49 Å)