9H6Z

AetF, a single-component flavin-dependent tryptophan halogenase, in complex with tryptoline

Summary for 9H6Z

Entry DOI	10.2210/pdb9h6z/pdb
Related	8CJD 8CJE 8CJF 8CJG
Descriptor	AetF, FLAVIN-ADENINE DINUCLEOTIDE, 2,3,4,9-tetrahydro-1~{H}-pyrido[3,4-b]indole, ... (6 entities in total)
Functional Keywords	single-component halogenase, tryptophan halogenase, non-native substrate, unnatural substrate, flavoprotein
Biological source	Aetokthonos hydrillicola Thurmond2011
Total number of polymer chains	2
Total formula weight	156705.15
Authors	Bork, S.,Niemann, H.H. (deposition date: 2024-10-25, release date: 2026-05-06)
Primary citation	Bork, S.,Horstmeier, H.J.,Scharkowski, B.,Niemann, H.H. Structural basis of regioselective double halogenation of the beta-carboline tryptoline by the single-component halogenase AetF To Be Published,
Experimental method	X-RAY DIFFRACTION (1.87 Å)

Structure validation