9H46

EGFR wild type in complex with 25328

This is a non-PDB format compatible entry.

Summary for 9H46

• Entry DOI: 10.2210/pdb9h46/pdb
• Descriptor: Epidermal growth factor receptor, 5-ethyl-2-[(2-methoxyphenyl)amino]-8-phenyl-pyrido[2,3-d]pyrimidin-7-one (3 entities in total)
• Functional Keywords: kinase, egfr, inhibitor, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 37807.75

Authors

Pintar, S.,Martin, M.P.,Noble, M.E.M. (deposition date: 2024-10-17, release date: 2024-12-04)

• Primary citation: Stewart, H.L.,Waring, M.J.; Covalent alkynylpyridopyrimidinones targeting cysteine 775 of the epidermal growth factor receptor overcome resistance to current therapies; To Be Published,

Experimental method

X-RAY DIFFRACTION (3.163 Å)