9GRW

Structure of Heparinase I from Bacteroides eggerthii in complex with calcium cofactor

Summary for 9GRW

• Entry DOI: 10.2210/pdb9grw/pdb
• Descriptor: Heparin lyase I, CALCIUM ION, ACETATE ION, ... (5 entities in total)
• Functional Keywords: heparin, heparan sulphate, heparinase, lyase, heparitinase
• Biological source: Bacteroides eggerthii
• Total number of polymer chains: 2
• Total formula weight: 90412.95

Authors

Mycroft-West, C.,Wu, L. (deposition date: 2024-09-12, release date: 2025-09-24, Last modification date: 2026-04-08)

• Primary citation: Kandola, T.K.,Mycroft-West, C.J.,Andrade De Lima, M.L.,Turner, A.,Gardini, C.,Urso, E.,Miller, G.,Bisio, A.,Yates, E.A.,Guerrini, M.,Wu, L.,Skidmore, M.A.; Enzymatic access to the rare Delta UA (1 - 4) Glc 3, 6, N-sulfated heparin disaccharide, implications for heparin quality control; Biorxiv, 2024; DOI: 10.1101/2024.09.26.615151

Experimental method

X-RAY DIFFRACTION (1.85 Å)