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9GKB

TRPC5 in complex with spin-labelled ligand SpinPico1

This is a non-PDB format compatible entry.
Summary for 9GKB
Entry DOI10.2210/pdb9gkb/pdb
EMDB information51416
DescriptorShort transient receptor potential channel 5, 7-[(4-chlorophenyl)methyl]-3-methyl-1-(3-oxidanylpropyl)-8-(2,2,6,6-tetramethyl-1-oxidanyl-piperidin-4-yl)oxy-purine-2,6-dione, CALCIUM ION, ... (4 entities in total)
Functional Keywordsmembrane protein, ion channel, inhibitor, non-covalent spin label, protein transport
Biological sourceHomo sapiens (human)
Total number of polymer chains4
Total formula weight360226.58
Authors
Porav, S.A.,Bon, R.S. (deposition date: 2024-08-23, release date: 2025-09-03)
Primary citationJohnson, A.J.,Porav, S.A.,Hammond, K.L.R.,Shah, A.,Hassane, E.M.,Pask, C.M.,Muench, S.P.,Wilson, A.J.,Pilotas, C.,Bon, R.S.
Non-covalent spin labelling of TRPC5 ion channels enables EPR studies of protein-ligand interactions
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.32 Å)
Structure validation

248636

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