9GJR

Crystal Structure of the Leishmania Bromodomain LmxBDF5.1 in complex with OXFBD06

This is a non-PDB format compatible entry.

Summary for 9GJR

• Entry DOI: 10.2210/pdb9gjr/pdb
• Descriptor: Bromo domain-containing protein, 5-[2-[5-(3,5-dimethyl-1,2-oxazol-4-yl)-1-[2-(4-ethanoylpiperazin-1-ium-1-yl)ethyl]benzimidazol-2-yl]ethyl]-2-methyl-benzenecarbonitrile, (R,R)-2,3-BUTANEDIOL, ... (5 entities in total)
• Functional Keywords: bromodomain, leishmania, protein-inhibitor complex, transcription
• Biological source: Leishmania mexicana
• Total number of polymer chains: 2
• Total formula weight: 26348.58

Authors

Amann, M.,Huegle, M.,Carter, J.,Einsle, O.,Guenther, S.,Conway, S. (deposition date: 2024-08-22, release date: 2025-09-03)

• Primary citation: Amann, M.,Huegle, M.,Carter, J.,Einsle, O.,Guenther, S.,Conway, S.; Crystal Structure of the Leishmania Bromodomain LmxBDF5.1 in complex with OXFBD06; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.45 Å)