9GEY

Crystal structure of CREBBP bromodomain in complex with (R,E)-2-methyl-1,2,3,5,9,10,11,12,18,19,22,23-dodecahydro-17H,21H-14,16-etheno-7,26-(metheno)[1,4]diazepino[2,3-l]pyrido[2,1-d][1]oxa[5,17]diazacycloicosine-4,8-dione

This is a non-PDB format compatible entry.

Summary for 9GEY

• Entry DOI: 10.2210/pdb9gey/pdb
• Related: 9GEJ 9GET 9GEU 9GEW
• Descriptor: CREBBP, (R,E)-2-methyl-1,2,3,5,9,10,11,12,18,19,22,23-dodecahydro-17H,21H-14,16-etheno-7,26-(metheno)[1,4]diazepino[2,3-l]pyrido[2,1-d][1]oxa[5,17]diazacycloicosine-4,8-dione, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: bromodomain, crebbp, protein-inhibitor complex, macrocycle, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 29461.99

Authors

Amann, M.,Boyd, A.,Einsle, O.,Guenther, S.,Moroglu, M.,Conway, S. (deposition date: 2024-08-07, release date: 2025-08-20)

• Primary citation: Amann, M.,Boyd, A.,Einsle, O.,Guenther, S.,Moroglu, M.,Conway, S.; Crystal structure of CREBBP bromodomain in complex with (R,E)-2-methyl-1,2,3,5,9,10,11,12,18,19,22,23-dodecahydro-17H,21H-14,16-etheno-7,26-(metheno)[1,4]diazepino[2,3-l]pyrido[2,1-d][1]oxa[5,17]diazacycloicosine-4,8-dione; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.56 Å)