9GEU

Crystal structure of CREBBP bromodomain in complex with (R,E)-2-methyl-1,2,3,5,10,11,17,18,21,22-decahydro-4H,16H,20H-13,15-etheno-7,25-(metheno)[1,4]diazepino[2,3-h]pyrido[1,2-p][1]oxa[4,16]diazacyclononadecine-4,8(9H)-dione

This is a non-PDB format compatible entry.

Summary for 9GEU

• Entry DOI: 10.2210/pdb9geu/pdb
• Related: 9GEJ 9GET
• Descriptor: CREBBP, (R,R)-2,3-BUTANEDIOL, (R,E)-2-methyl-1,2,3,5,10,11,17,18,21,22-decahydro-4H,16H,20H-13,15-etheno-7,25-(metheno)[1,4]diazepino[2,3-h]pyrido[1,2-p][1]oxa[4,16]diazacyclononadecine-4,8(9H)-dione, ... (5 entities in total)
• Functional Keywords: bromodomain, crebbp, protein-inhibitor complex, transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 29830.32

Authors

Amann, M.,Boyd, A.,Einsle, O.,Guenther, S.,Moroglu, M.,Conway, S. (deposition date: 2024-08-07, release date: 2025-08-20)

• Primary citation: Amann, M.,Boyd, A.,Guenther, S.,Einsle, O.,Moroglu, M.,Conway, S.; Crystal structure of the human CREBBP bromodomain in complex with (R,E)-2-methyl-1,2,3,5,10,11,17,18,21,22-decahydro-4H,16H,20H-13,15-etheno-7,25-(metheno)[1,4]diazepino[2,3-h]pyrido[1,2-p][1]oxa[4,16]diazacyclononadecine-4,8(9H)-dione; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.56 Å)