9GE9
Trp-cage fortified Tc5b-Exenatide chimera (Ex-4-Tc5bQR) at 277K
Summary for 9GE9
| Entry DOI | 10.2210/pdb9ge9/pdb |
| Descriptor | Trp-cage fortified Tc5b-Exenatide chimera (Ex-4-Tc5bQR) (1 entity in total) |
| Functional Keywords | exenatide, glp-1r ligand, trp-cage de novo protein, miniprotein, disulfide bond, de novo protein |
| Biological source | Heloderma suspectum |
| Total number of polymer chains | 1 |
| Total formula weight | 2785.09 |
| Authors | Horvath, D. (deposition date: 2024-08-07, release date: 2024-09-25, Last modification date: 2024-10-09) |
| Primary citation | Horvath, D.,Straner, P.,Taricska, N.,Fazekas, Z.,Menyhard, D.K.,Perczel, A. Influence of Trp-Cage on the Function and Stability of GLP-1R Agonist Exenatide Derivatives. J.Med.Chem., 67:16757-16772, 2024 Cited by PubMed: 39254428DOI: 10.1021/acs.jmedchem.4c01553 PDB entries with the same primary citation |
| Experimental method | SOLUTION NMR |
Structure validation
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