9GDG

Crystal structure of TRIM24 PHD-BRD in complex with N-(2-(2-(2-acetamidoethoxy)ethoxy)ethyl)-3-(N-(1,3-dimethyl-2-oxo-6-(3-propoxyphenoxy)-2,3-dihydro-1H-benzo[d]imidazol-5-yl)sulfamoyl)benzamide (PEG linker unresolved)

This is a non-PDB format compatible entry.

Summary for 9GDG

• Entry DOI: 10.2210/pdb9gdg/pdb
• Descriptor: Transcription intermediary factor 1-alpha, N-(2-(2-(2-acetamidoethoxy)ethoxy)ethyl)-3-(N-(1,3-dimethyl-2-oxo-6-(3-propoxyphenoxy)-2,3-dihydro-1H-benzo[d]imidazol-5-yl)sulfamoyl)benzamide, ZINC ION, ... (4 entities in total)
• Functional Keywords: transcriptional regulation, phd, bromodomain, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 22296.18

Authors

Platt, M.A.,Kot, E.,Conway, S.J.,Koekemoer, L. (deposition date: 2024-08-05, release date: 2025-08-13)

• Primary citation: Platt, M.A.,Kot, E.,Conway, S.J.,Koekemoer, L.; Crystal structure of TRIM24 PHD-BRD in complex with N-(2-(2-(2-acetamidoethoxy)ethoxy)ethyl)-3-(N-(1,3-dimethyl-2-oxo-6-(3-propoxyphenoxy)-2,3-dihydro-1H-benzo[d]imidazol-5-yl)sulfamoyl)benzamide (PEG linker unresolved); To Be Published,

Experimental method

X-RAY DIFFRACTION (1.462 Å)