9GCP

ChREBP/14-3-3 complex stabilized by AMP

Summary for 9GCP

Entry DOI	10.2210/pdb9gcp/pdb
Descriptor	14-3-3 protein beta/alpha, N-terminally processed, Carbohydrate-responsive element-binding protein, ADENOSINE MONOPHOSPHATE (3 entities in total)
Functional Keywords	amp, carbohydrate and lipid homeostasis, lipogenesis, chrebp, transcription factor, allosteric regulation, transcription
Biological source	Homo sapiens (human) More
Total number of polymer chains	8
Total formula weight	117752.24
Authors	Moschref, M.,Heimhalt, M.,Pysik, T.,Menzer, W.M.,Basquin, J.,Margulies, C.E.,Ladurner, A.G. (deposition date: 2024-08-02, release date: 2025-08-13)
Primary citation	Moschref, M.,Heimhalt, M.,Pysik, T.,Menzer, W.M.,Basquin, J.,Margulies, C.E.,Ladurner, A.G. Glucose-6-phosphate functions as a selective receptor agonist for the sugar tolerance transcription factor ChREBP To Be Published,
Experimental method	X-RAY DIFFRACTION (2.59 Å)

Structure validation