9G4S

Crystal structure of the human METTL3-METTL14 in complex with small molecule inhibitor Compound 56

This is a non-PDB format compatible entry.

Summary for 9G4S

• Entry DOI: 10.2210/pdb9g4s/pdb
• Descriptor: N6-adenosine-methyltransferase catalytic subunit, N6-adenosine-methyltransferase non-catalytic subunit, 4-[(3~{R})-3-(cyclopropylmethylamino)piperidin-1-yl]-1-[(1~{R})-1-[4-[5-(dimethylamino)pyridin-3-yl]-1,2,3-triazol-1-yl]ethyl]pyridin-2-one, ... (6 entities in total)
• Functional Keywords: mettl3 mettl14 inhibitor epics, rna binding protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 57975.44

Authors

Dutheuil, G.,Oukoloff, K. (deposition date: 2024-07-16, release date: 2025-02-12)

• Primary citation: Dutheuil, G.,Oukoloff, K.; Crystal structure of the human METTL3-METTL14 in complex with small molecule inhibitor Compound 56; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)