9G08

Structure of human RNF213 bound to the secreted effector IpaH1.4 from Shigella flexneri

Summary for 9G08

Entry DOI	10.2210/pdb9g08/pdb
EMDB information	50913
Descriptor	E3 ubiquitin-protein ligase RNF213, E3 ubiquitin-protein ligase IpaH1.4, ADENOSINE-5'-TRIPHOSPHATE, ... (5 entities in total)
Functional Keywords	rnf213, ipah1.4, ipah, e3 ligase, ring, lrr, nel, secreted effector, shigella, inhibitor, complex, aaa atpase, antimicrobial protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	2
Total formula weight	662103.06
Authors	Naydenova, K.,Randow, F. (deposition date: 2024-07-07, release date: 2025-04-16)
Primary citation	Naydenova, K.,Boyle, K.B.,Pathe, C.,Pothukuchi, P.,Crespillo-Casado, A.,Otten, E.G.,Hammoudi, P.-M.,Randow, F. Shigella flexneri evades LPS ubiquitylation through IpaH1.4-mediated degradation of RNF213 To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.3 Å)

Structure validation