9FYD

tubulin - cryptophycin-uD[Dab] complex

This is a non-PDB format compatible entry.

Summary for 9FYD

• Entry DOI: 10.2210/pdb9fyd/pdb
• Descriptor: Tubulin alpha-1B chain, cryptophycin-uD[Dab], PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (12 entities in total)
• Functional Keywords: cell cycle, cytoskeleton, microtubule, tubulin, cryptophycin, microtubule targting agent
• Biological source: Rattus norvegicus (Norway rat); More
• Total number of polymer chains: 6
• Total formula weight: 265856.73

Authors

Dessin, C.,Schachtsiek, T.,Voss, J.,Abel, A.-C.,Neumann, B.,Stammler, H.-G.,Prota, A.E.,Sewald, N. (deposition date: 2024-07-03, release date: 2024-10-09)

• Primary citation: Dessin, C.,Schachtsiek, T.,Voss, J.,Abel, A.C.,Neumann, B.,Stammler, H.G.,Prota, A.E.,Sewald, N.; Highly Cytotoxic Cryptophycin Derivatives with Modification in Unit D for Conjugation.; Angew.Chem.Int.Ed.Engl., :e202416210-e202416210, 2024; PubMed: 39324938; DOI: 10.1002/anie.202416210

Experimental method

X-RAY DIFFRACTION (2.3 Å)