9FVO
The HIV protease inhibitor amprenavir binding to the active site of Cryphonectria parasitica endothiapepsin
Summary for 9FVO
Entry DOI | 10.2210/pdb9fvo/pdb |
Descriptor | Endothiapepsin, {3-[(4-AMINO-BENZENESULFONYL)-ISOBUTYL-AMINO]-1-BENZYL-2-HYDROXY-PROPYL}-CARBAMIC ACID TETRAHYDRO-FURAN-3-YL ESTER, TETRAETHYLENE GLYCOL, ... (7 entities in total) |
Functional Keywords | aspartic protease, drug development, inhibitor, x-ray crystallographic screening, chestnut blight fungus, protease model., hydrolase |
Biological source | Cryphonectria parasitica (chestnut blight fungus) |
Total number of polymer chains | 1 |
Total formula weight | 35508.81 |
Authors | Falke, S.,Senst, J.M.,Guenther, S.,Meents, A. (deposition date: 2024-06-27, release date: 2024-07-10) |
Primary citation | Falke, S.,Senst, J.M.,Guenther, S.,Meents, A. The HIV protease inhibitor amprenavir binding to the active site of Cryphonectria parasitica endothiapepsin To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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