9FRW

Yeast 20S proteasome with human beta1i (1-51)

Summary for 9FRW

• Entry DOI: 10.2210/pdb9frw/pdb
• Related: 5CZ4
• Descriptor: Proteasome subunit alpha type-2, Proteasome subunit beta type-4, Proteasome subunit beta type-5, ... (19 entities in total)
• Functional Keywords: proteasome, mutant, human chimeric subunit, protein engineering, hydrolase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 28
• Total formula weight: 731805.79

Authors

Maurits, E.,Huber, E.M.,Dekker, P.M.,Wang, X.,Heinemeyer, W.,Florea, B.I.,Groll, M.,Overkleeft, H.S. (deposition date: 2024-06-19, release date: 2025-04-30, Last modification date: 2025-09-10)

• Primary citation: Maurits, E.,Huber, E.M.,Dekker, P.M.,Wang, X.,Heinemeyer, W.,Florea, B.I.,Groll, M.,Overkleeft, H.S.; Structure-based design of peptide epoxyketones selectively targeting the three human immunoproteasome active sites; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.85 Å)