9FRM

The crystal structure of glycogen phosphorylase with an indole derivative

This is a non-PDB format compatible entry.

Summary for 9FRM

• Entry DOI: 10.2210/pdb9frm/pdb
• Descriptor: Glycogen phosphorylase, muscle form, (7~{S})-1-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)amino]-6,6-dimethyl-7-oxidanyl-7,8-dihydrobenzo[cd]indole-3-carboxylic acid, DIMETHYL SULFOXIDE, ... (4 entities in total)
• Functional Keywords: transferase
• Biological source: Oryctolagus cuniculus (rabbit)
• Total number of polymer chains: 1
• Total formula weight: 99455.26

Authors

Koulas, S.M.,Leonidas, D.D. (deposition date: 2024-06-19, release date: 2025-05-07)

• Primary citation: Arunrattiyakorn, P.,Juiprasert, C.,Koulas, S.M.,Boonsri, P.,Aree, T.,Yagi-Utsumi, M.,Kato, K.,Leonidas, D.D.; Synthesis and evaluation of tetrahydrobenzo[cd]indole derivatives as glycogen phosphorylase inhibitors; Med.Chem.Res., 2025; DOI: 10.1007/s00044-025-03384-7

Experimental method

X-RAY DIFFRACTION (2 Å)