9FM0
Human antibody (Fab) and P. aeruginosa (T3SS) protein PcrV-fragment complex
Summary for 9FM0
| Entry DOI | 10.2210/pdb9fm0/pdb |
| Descriptor | Human Fab Heavy Chain (FabHC) V-region, Human Fab Light Chain (FabLC) V-region, Type III secretion protein PcrV, ... (6 entities in total) |
| Functional Keywords | human antibodies, type iii secretion system, pcrv, virulence, pseudomonas, bacterial infection, antimicrobials, anti-virulence, mab, amr, immune system |
| Biological source | Homo sapiens More |
| Total number of polymer chains | 6 |
| Total formula weight | 123635.24 |
| Authors | Desveaux, J.M.,Contreras Martel, C.,Dessen, A. (deposition date: 2024-06-05, release date: 2025-06-18) |
| Primary citation | Desveaux, J.M.,Faudry, E.,Contreras-Martel, C.,Cretin, F.,Dergan-Dylon, S.,Amen, A.,Bally, I.,Tardivy-Casemajor, V.,Chenavier, F.,Caspar, Y.,Attree, I.,Dessen, A.,Poignard, P. Human antibodies that target the Type III Secretion System of Pseudomonas aeruginosa inhibit translocon function and cytotoxicity To Be Published, |
| Experimental method | X-RAY DIFFRACTION (2.56 Å) |
Structure validation
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