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9FM0

Human antibody (Fab) and P. aeruginosa (T3SS) protein PcrV-fragment complex

Summary for 9FM0
Entry DOI10.2210/pdb9fm0/pdb
DescriptorHuman Fab Heavy Chain (FabHC) V-region, Human Fab Light Chain (FabLC) V-region, Type III secretion protein PcrV, ... (6 entities in total)
Functional Keywordshuman antibodies, type iii secretion system, pcrv, virulence, pseudomonas, bacterial infection, antimicrobials, anti-virulence, mab, amr, immune system
Biological sourceHomo sapiens
More
Total number of polymer chains6
Total formula weight123635.24
Authors
Desveaux, J.M.,Contreras Martel, C.,Dessen, A. (deposition date: 2024-06-05, release date: 2025-06-18)
Primary citationDesveaux, J.M.,Faudry, E.,Contreras-Martel, C.,Cretin, F.,Dergan-Dylon, S.,Amen, A.,Bally, I.,Tardivy-Casemajor, V.,Chenavier, F.,Caspar, Y.,Attree, I.,Dessen, A.,Poignard, P.
Human antibodies that target the Type III Secretion System of Pseudomonas aeruginosa inhibit translocon function and cytotoxicity
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.56 Å)
Structure validation

246704

PDB entries from 2025-12-24

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