9FJH
Two PLK1 PBD proteins bound to CENP-U(58-114) phosphorylated at Thr78 and Thr98
Summary for 9FJH
Entry DOI | 10.2210/pdb9fjh/pdb |
Descriptor | Serine/threonine-protein kinase PLK1, Centromere protein U, TRIETHYLENE GLYCOL, ... (6 entities in total) |
Functional Keywords | plk1, cell cycle, ccan, kinase, mitosis, kinetochore, cenp-u, phosphorylation |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 67175.55 |
Authors | Ren, L.,Gasper, R.,Vetter, I.R.,Musacchio, A. (deposition date: 2024-05-31, release date: 2025-09-24) |
Primary citation | Ren, L.,Gasper, R.,Vetter, I.R.,Musacchio, A. Structural and molecular basis of kinaseregulated inner-kinetochore recruitment of PLK1 by CENP-U To be published, |
Experimental method | X-RAY DIFFRACTION (2.15 Å) |
Structure validation
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