9FFX

Cryo-EM structure of the alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Nb38 in the short-lived asymmetric pre-active state

This is a non-PDB format compatible entry.

Summary for 9FFX

• Entry DOI: 10.2210/pdb9ffx/pdb
• EMDB information: 50377
• Descriptor: Gamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit beta-3, Isoform 1 of Gamma-aminobutyric acid receptor subunit gamma-2, ... (9 entities in total)
• Functional Keywords: gaba, neurotransmission, gating cycle, time-resolved cryo-em, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 249265.65

Authors

Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R. (deposition date: 2024-05-23, release date: 2025-06-04)

• Primary citation: Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R.; Cryo-EM structure of the alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Nb38 in the short-lived asymmetric pre-active state; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.6 Å)