9FFW

Cryo-EM structure of the alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Nb38 in the short-lived symmetric pre-active state

Summary for 9FFW

• Entry DOI: 10.2210/pdb9ffw/pdb
• EMDB information: 50376
• Descriptor: Gamma-aminobutyric acid receptor subunit alpha-1, DECANE, Gamma-aminobutyric acid receptor subunit beta-3, ... (10 entities in total)
• Functional Keywords: gaba, neurotransmission, gating cycle, time-resolved cryo-em, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 250080.18

Authors

Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R. (deposition date: 2024-05-23, release date: 2025-06-04)

• Primary citation: Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R.; Cryo-EM structure of the alpha1beta3gamma2 GABA(A) receptor in complex with GABA and Nb38 in the short-lived symmetric pre-active state; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.4 Å)