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9FFP

Cryo-EM structure of the alpha1beta3 GABA(A) receptor in complex with GABA and Mb25 in the short-lived asymmetric open state of branch 1

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Summary for 9FFP
Entry DOI10.2210/pdb9ffp/pdb
EMDB information50369
DescriptorGamma-aminobutyric acid receptor subunit alpha-1, Gamma-aminobutyric acid receptor subunit beta-3, Megabody25,Outer membrane protein, ... (6 entities in total)
Functional Keywordsgaba, neurotransmission, gating cycle, time-resolved cryo-em, membrane protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains6
Total formula weight293383.22
Authors
Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R. (deposition date: 2024-05-23, release date: 2025-06-04)
Primary citationMihaylov, D.B.,Malinauskas, T.,Aricescu, A.R.
Cryo-EM structure of the alpha1beta3 GABA(A) receptor in complex with GABA and Mb25 in the short-lived asymmetric open state of branch 1
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.5 Å)
Structure validation

237423

PDB entries from 2025-06-11

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