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9FFL

Cryo-EM structure of the alpha1beta3 GABA(A) receptor in complex with GABA and Mb25 in the short-lived symmetric pre-active state

Summary for 9FFL
Entry DOI10.2210/pdb9ffl/pdb
EMDB information50365
DescriptorGamma-aminobutyric acid receptor subunit alpha-1, HEXADECANE, Gamma-aminobutyric acid receptor subunit beta-3, ... (11 entities in total)
Functional Keywordsgaba, neurotransmission, gating cycle, time-resolved cryo-em, membrane protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains6
Total formula weight296054.41
Authors
Mihaylov, D.B.,Malinauskas, T.,Aricescu, A.R. (deposition date: 2024-05-23, release date: 2025-06-04)
Primary citationMihaylov, D.B.,Malinauskas, T.,Aricescu, A.R.
Cryo-EM structure of the alpha1beta3 GABA(A) receptor in complex with GABA and Mb25 in the short-lived symmetric pre-active state
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.8 Å)
Structure validation

236963

PDB entries from 2025-06-04

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