9FCS
CysG(N-16)-H122N mutant in complex with SAH from Kitasatospora cystarginea
Summary for 9FCS
Entry DOI | 10.2210/pdb9fcs/pdb |
Related | 9FCD |
Descriptor | SAM-dependent methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 1,2-ETHANEDIOL, ... (4 entities in total) |
Functional Keywords | natural product biosynthesis, enzyme mechanism, metal ion interaction, molecular docking, structure function relationships, transferase |
Biological source | Kitasatospora cystarginea |
Total number of polymer chains | 2 |
Total formula weight | 48826.85 |
Authors | Kuttenlochner, W.,Beller, P.,Kaysser, L.,Groll, M. (deposition date: 2024-05-15, release date: 2024-08-21, Last modification date: 2024-09-18) |
Primary citation | Kuttenlochner, W.,Beller, P.,Kaysser, L.,Groll, M. Deciphering the SAM- and metal-dependent mechanism of O-methyltransferases in cystargolide and belactosin biosynthesis: A structure-activity relationship study. J.Biol.Chem., 300:107646-107646, 2024 Cited by PubMed: 39121999DOI: 10.1016/j.jbc.2024.107646 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.6 Å) |
Structure validation
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