9FCS

CysG(N-16)-H122N mutant in complex with SAH from Kitasatospora cystarginea

Summary for 9FCS

• Entry DOI: 10.2210/pdb9fcs/pdb
• Related: 9FCD
• Descriptor: SAM-dependent methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, 1,2-ETHANEDIOL, ... (4 entities in total)
• Functional Keywords: natural product biosynthesis, enzyme mechanism, metal ion interaction, molecular docking, structure function relationships, transferase
• Biological source: Kitasatospora cystarginea
• Total number of polymer chains: 2
• Total formula weight: 48826.85

Authors

Kuttenlochner, W.,Beller, P.,Kaysser, L.,Groll, M. (deposition date: 2024-05-15, release date: 2024-08-21)

• Primary citation: Kuttenlochner, W.,Beller, P.,Kaysser, L.,Groll, M.; Deciphering the SAM- and Metal-Dependent Mechanism of O-Methyltransferases in Cystargolide and Belactosin Biosynthesis: A Structure-Activity Relationship Study.; J.Biol.Chem., :107646-107646, 2024; PubMed: 39121999; DOI: 10.1016/j.jbc.2024.107646

Experimental method