9FAV

CryoEM structure of human full-length beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2 and Megabody25, in a closed state (StateC2)

This is a non-PDB format compatible entry.

Summary for 9FAV

• Entry DOI: 10.2210/pdb9fav/pdb
• EMDB information: 50283
• Descriptor: Gamma-aminobutyric acid receptor subunit beta-3, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (18 entities in total)
• Functional Keywords: gaba, neurotransmission, ternary complex, inhibitory synapse, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 10
• Total formula weight: 453816.82

Authors

Kasaragod, V.B.,Aricescu, A.R. (deposition date: 2024-05-10, release date: 2025-07-02)

• Primary citation: Kasaragod, V.B.,Aricescu, A.R.; CryoEM structure of human full-length beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2 and Megabody25, in a closed state (StateC2); To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.2 Å)