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9FAU

CryoEM structure of human full-length beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2 and Megabody25, in a closed state (StateC1)

Summary for 9FAU
Entry DOI10.2210/pdb9fau/pdb
EMDB information50282
DescriptorGamma-aminobutyric acid receptor subunit beta-3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEXANE, ... (18 entities in total)
Functional Keywordsgaba, neurotransmission, ternary complex, inhibitory synapse, membrane protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains10
Total formula weight455802.13
Authors
Kasaragod, V.B.,Aricescu, A.R. (deposition date: 2024-05-10, release date: 2025-07-02)
Primary citationKasaragod, V.B.,Aricescu, A.R.
CryoEM structure of human full-length beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2 and Megabody25, in a closed state (StateC1)
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.1 Å)
Structure validation

248636

건을2026-02-04부터공개중

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