9FAU

CryoEM structure of human full-length beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2 and Megabody25, in a closed state (StateC1)

Summary for 9FAU

Entry DOI	10.2210/pdb9fau/pdb
EMDB information	50282
Descriptor	Gamma-aminobutyric acid receptor subunit beta-3, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, HEXANE, ... (18 entities in total)
Functional Keywords	gaba, neurotransmission, ternary complex, inhibitory synapse, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	10
Total formula weight	455802.13
Authors	Kasaragod, V.B.,Aricescu, A.R. (deposition date: 2024-05-10, release date: 2025-07-02)
Primary citation	Kasaragod, V.B.,Aricescu, A.R. CryoEM structure of human full-length beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2 and Megabody25, in a closed state (StateC1) To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation