9FAK

CryoEM structure of human full-length alpha1beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38 in a desensitised state (StateD2)

9FAK の概要

• エントリーDOI: 10.2210/pdb9fak/pdb
• EMDBエントリー: 50274
• 分子名称: Gamma-aminobutyric acid receptor subunit alpha-1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (23 entities in total)
• 機能のキーワード: gaba, neurotransmission, ternary complex, inhibitory postsynapse, membrane protein
• 由来する生物種: Homo sapiens (human); 詳細
• タンパク質・核酸の鎖数: 9
• 化学式量合計: 404286.14

構造登録者

Kasaragod, V.B.,Aricescu, A.R. (登録日: 2024-05-10, 公開日: 2025-07-02)

• 主引用文献: Kasaragod, V.B.,Aricescu, A.R.; CryoEM structure of human full-length alpha1beta3gamma2 GABA(A) receptor in complex with GARLH4, the TMD of Neuroligin2, GABA and Megabody38 in a desensitised state (StateD2); To Be Published,

実験手法

ELECTRON MICROSCOPY (2.6 Å)