9F77

BAZ2A bromodomain in complex with acetylpyrrole derivative compound 27-TND19

This is a non-PDB format compatible entry.

Summary for 9F77

• Entry DOI: 10.2210/pdb9f77/pdb
• Related: 9F6W 9F70 9F71
• Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, 4-ethanoyl-~{N}-[(1~{S},2~{R})-2-[4-(hydroxymethyl)-1,2,3-triazol-1-yl]cyclohexyl]-3,5-dimethyl-1~{H}-pyrrole-2-carboxamide (3 entities in total)
• Functional Keywords: four helical bundle, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 3
• Total formula weight: 38554.27

Authors

Dalle Vedove, A.,Cazzanelli, G.,Caflisch, A.,Lolli, G. (deposition date: 2024-05-03, release date: 2025-05-14)

• Primary citation: Dalle Vedove, A.,Cazzanelli, G.,D'Agostino, V.G.,Caflisch, A.,Lolli, G.; Unusual backfolded binding poses of BAZ2A bromodomain binders; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.42 Å)