9F71

BAZ2A bromodomain in complex with acetylpyrrole derivative compound 26-TND18

This is a non-PDB format compatible entry.

Summary for 9F71

• Entry DOI: 10.2210/pdb9f71/pdb
• Related: 9F6W 9F70
• Descriptor: Bromodomain adjacent to zinc finger domain protein 2A, 1-[2,4-dimethyl-5-[(3~{R})-3-[4-(pyrrolidin-1-ylmethyl)-1~{H}-pyrazol-3-yl]piperidin-1-yl]carbonyl-1~{H}-pyrrol-3-yl]ethanone, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: four helical bundle, transcription
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 12847.76

Authors

Dalle Vedove, A.,Cazzanelli, G.,Caflisch, A.,Lolli, G. (deposition date: 2024-05-02, release date: 2025-05-14)

• Primary citation: Dalle Vedove, A.,Cazzanelli, G.,D'Agostino, V.G.,Caflisch, A.,Lolli, G.; Unusual backfolded binding poses of BAZ2A bromodomain binders; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.35 Å)