9F77
BAZ2A bromodomain in complex with acetylpyrrole derivative compound 27-TND19
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C (A, B, C) | Bromodomain adjacent to zinc finger domain protein 2A | polymer | 106 | 12492.0 | 3 | UniProt (Q9UIF9) Pfam (PF00439) | Homo sapiens (human) | Transcription termination factor I-interacting protein 5,TTF-I-interacting protein 5,Tip5,hWALp3 |
| 2 | D, E, F (A, B, C) | 4-ethanoyl-~{N}-[(1~{S},2~{R})-2-[4-(hydroxymethyl)-1,2,3-triazol-1-yl]cyclohexyl]-3,5-dimethyl-1~{H}-pyrrole-2-carboxamide | non-polymer | 359.4 | 3 | Chemie (A1H99) | |||
| 3 | G, H, I (A, B, C) | water | water | 18.0 | 392 | Chemie (HOH) |
Sequence modifications
A, B, C: 1796 - 1899 (UniProt: Q9UIF9)
| PDB | External Database | Details |
|---|---|---|
| Ser 1794 | - | expression tag |
| Met 1795 | - | expression tag |
| His 1845 | Glu 1845 | engineered mutation |
| Ser 1848 | Leu 1848 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 37476.0 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1078.3 | |
| All* | Total formula weight | 38554.3 |
