9F6B

Human neuropilin-1 in a complex with a quinoline based antagonists

This is a non-PDB format compatible entry.

Summary for 9F6B

• Entry DOI: 10.2210/pdb9f6b/pdb
• Descriptor: Neuropilin-1, (2~{S})-2-[[3-[[6-[3-(aminomethyl)phenyl]quinolin-8-yl]sulfonylamino]thiophen-2-yl]carbonylamino]-5-carbamimidamido-pentanoic acid (3 entities in total)
• Functional Keywords: nrp-1 small molecule antagonist pain transmission, signaling protein
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 37025.97

Authors

Djordjevic, S.,Selwood, D.,Hubbard, P.,Leonard, P.,Mota, F. (deposition date: 2024-04-30, release date: 2025-05-14)

• Primary citation: Mota, F.,Selwood, D.; Quinoline based neuropilin-1 antagonists exhibit a pure antagonist profile and block pain transmission; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.57 Å)