9F43
cryo-EM structure of human LST2 bound to human mTOR complex 1, focused on RAPTOR
Summary for 9F43
Entry DOI | 10.2210/pdb9f43/pdb |
EMDB information | 50182 |
Descriptor | Regulatory-associated protein of mTOR, Lateral signaling target protein 2 homolog (2 entities in total) |
Functional Keywords | mtor, mtorc1, lst2, zfyve28, egfr, tos, signaling protein |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 2 |
Total formula weight | 249369.13 |
Authors | |
Primary citation | Battaglioni, S.,Craigie, L.M.,Filippini, S.,Maier, T.,Hall, M.N. mTORC1 phosphorylates and stabilizes LST2 to negatively regulate EGFR Proc.Natl.Acad.Sci.USA, 2024 |
Experimental method |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)