9F2F

Carbonic anhydrase II variant with bound iron complex in space group R3 (ArPase)

This is a non-PDB format compatible entry.

Summary for 9F2F

• Entry DOI: 10.2210/pdb9f2f/pdb
• Descriptor: Carbonic anhydrase 2, 4,4,7,10,10-pentamethyl-3,6,8,11-tetrakis(oxidanylidene)-N-[2-(4-sulfamoylphenyl)ethyl]-2,5,7,9,12-pentazabicyclo[11.4.0]heptadeca-1(13),14,16-triene-15-carboxamide containing iron, ZINC ION, ... (5 entities in total)
• Functional Keywords: artificial enzyme, metalloenzyme, peroxidase, human carbonic anhydrase, oxidoreductase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 4
• Total formula weight: 121291.90

Authors

Jakob, R.P.,Ward, T.R. (deposition date: 2024-04-23, release date: 2025-03-05)

• Primary citation: Morita, I.,Faraone, A.,Salvisberg, E.,Zhang, K.,Jakob, R.P.,Maier, T.,Ward, T.R.; Directed Evolution of an Artificial Hydroxylase Based on a Thermostable Human Carbonic Anhydrase Protein; Acs Catalysis, 14:17171-17179, 2024; DOI: 10.1021/acscatal.4c04163

Experimental method

X-RAY DIFFRACTION (1.52 Å)