9EZJ
Apo human TDO in complex with a bound inhibitor (Cpd-4)
This is a non-PDB format compatible entry.
Summary for 9EZJ
Entry DOI | 10.2210/pdb9ezj/pdb |
Descriptor | Tryptophan 2,3-dioxygenase, alpha-methyl-L-tryptophan, ethyl (9~{R})-2-methoxy-4-oxidanylidene-9-[[(1~{S})-1-phenylethyl]-[(2-propan-2-ylphenyl)carbamoyl]amino]-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidine-3-carboxylate, ... (4 entities in total) |
Functional Keywords | apo-tdo, heme, inhibitor, oxidoreductase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 4 |
Total formula weight | 193992.05 |
Authors | |
Primary citation | Lotz-Jenne, C.,lange, R.,Cren, S.,Bourquin, G.,Goglia, L.,Kimmerlin, T.,Wicki, M.,Mueller, M.,Artico, N.,Ackerknecht, S.,Joesch, C.,Mac Sweeney, A. Discovery and binding mode of small molecule inhibitors of the apo form of human TDO2 To Be Published, |
Experimental method |
Structure validation
Download full validation report![Download](/newweb/media/icons/dl.png)
![Download](/newweb/media/icons/dl.png)