9EY9

Yeast 20S proteasome in complex with a sybactin derivative (PheSyr)

This is a non-PDB format compatible entry.

Summary for 9EY9

• Entry DOI: 10.2210/pdb9ey9/pdb
• Related: 4FZC
• Descriptor: Proteasome subunit alpha type-2, Proteasome subunit beta type-4, proteasome endopeptidase complex, ... (16 entities in total)
• Functional Keywords: hydrolase-hydrolase inhibitor complex, proteasome, syrbactins, natural product derivative, binding analysis, hydrolase
• Biological source: Saccharomyces cerevisiae (brewer's yeast); More
• Total number of polymer chains: 28
• Total formula weight: 733255.80

Authors

Praeve, L.,Kuttenlochner, W.,Tabak, W.W.A.,Langer, C.,Kaiser, M.,Groll, M.,Bode, H.B. (deposition date: 2024-04-09, release date: 2025-02-19)

• Primary citation: Prave, L.,Kuttenlochner, W.,Tabak, W.W.,Langer, C.,Kaiser, M.,Groll, M.,Bode, H.B.; Bioengineering of syrbactin megasynthetases for immunoproteasome inhibitor production; Chem, 10:3212-3223, 2024; DOI: 10.1016/j.chempr.2024.07.013

Experimental method

X-RAY DIFFRACTION (3.1 Å)