9EY8

Crystal structure of human tyrosinase-related protein 1 (TYRP1) in complex with (s)-amino-L-tyrosine

これはPDB形式変換不可エントリーです。

9EY8 の概要

• エントリーDOI: 10.2210/pdb9ey8/pdb
• 分子名称: 5,6-dihydroxyindole-2-carboxylic acid oxidase, alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-L-fucopyranose-(1-6)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (16 entities in total)
• 機能のキーワード: melanogenesis, human tyrosinase, tyrosinase inhibitor, metal binding protein
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 223727.82

構造登録者

Ng, Y.M.,Soler-Lopez, M. (登録日: 2024-04-09, 公開日: 2024-05-01, 最終更新日: 2024-07-03)

• 主引用文献: Faure, C.,Min Ng, Y.,Belle, C.,Soler-Lopez, M.,Khettabi, L.,Saidi, M.,Berthet, N.,Maresca, M.,Philouze, C.,Rachidi, W.,Reglier, M.,du Moulinet d'Hardemare, A.,Jamet, H.; Interactions of Phenylalanine Derivatives with Human Tyrosinase: Lessons from Experimental and Theoretical tudies.; Chembiochem, 25:e202400235-e202400235, 2024; PubMed: 38642076; DOI: 10.1002/cbic.202400235

実験手法

X-RAY DIFFRACTION (2.2 Å)