9EUP
Inhibitor-free outward-open structure of Drosophila dopamine transporter
Summary for 9EUP
Entry DOI | 10.2210/pdb9eup/pdb |
Related | 9EUO |
EMDB information | 19978 19979 |
Descriptor | Sodium-dependent dopamine transporter, 9D5 ANTIBODY, HEAVY CHAIN, 9D5 ANTIBODY, LIGHT CHAIN, ... (8 entities in total) |
Functional Keywords | slc6a3, dopamine transporter, neurotransmitter sodium symporters, membrane protein |
Biological source | Drosophila melanogaster (fruit fly) More |
Total number of polymer chains | 3 |
Total formula weight | 113778.42 |
Authors | Pedersen, C.N.,Yang, F.,Ita, S.,Xu, Y.,Akunuri, R.,Trampari, S.,Neumann, C.M.T.,Desdorf, L.M.,Schioett, B.,Salvino, J.M.,Mortensen, O.V.,Nissen, P.,Shahsavar, A. (deposition date: 2024-03-27, release date: 2024-07-24) |
Primary citation | Pedersen, C.N.,Yang, F.,Ita, S.,Xu, Y.,Akunuri, R.,Trampari, S.,Neumann, C.M.T.,Desdorf, L.M.,Schiott, B.,Salvino, J.M.,Mortensen, O.V.,Nissen, P.,Shahsavar, A. Cryo-EM structure of the dopamine transporter with a novel atypical non-competitive inhibitor bound to the orthosteric site. J.Neurochem., 2024 Cited by PubMed: 39010681DOI: 10.1111/jnc.16179 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3 Å) |
Structure validation
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