9ET9
CDK2-cyclin A in complex with FragLite 4
Summary for 9ET9
Entry DOI | 10.2210/pdb9et9/pdb |
Descriptor | Cyclin-A2, Cyclin-dependent kinase 2, 4-bromanylpyridin-2-amine, ... (4 entities in total) |
Functional Keywords | cyclin-dependent kinase, fraglite, cdk2, cyclin a, fragment, cell cycle |
Biological source | Bos taurus (cattle) More |
Total number of polymer chains | 4 |
Total formula weight | 132074.60 |
Authors | Hope, I.,Martin, M.P.,Waring, M.J.,Noble, M.E.M.,Endicott, J.A.,Tatum, N.J. (deposition date: 2024-03-26, release date: 2025-04-09) |
Primary citation | Hope, I.,Martin, M.P.,Waring, M.J.,Noble, M.E.M.,Endicott, J.A.,Tatum, N.J. Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction To Be Published, |
Experimental method | X-RAY DIFFRACTION (2.494 Å) |
Structure validation
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