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9ESW

CDK2-cyclin A in complex with FragLite 18

Summary for 9ESW
Entry DOI10.2210/pdb9esw/pdb
DescriptorCyclin-dependent kinase 2, Cyclin-A2, (4-bromanylpyridin-2-yl)methanol, ... (4 entities in total)
Functional Keywordscyclin-dependent kinase, fraglite, cdk2, cyclin a, fragment, cell cycle
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight132600.75
Authors
Hope, I.,Martin, M.P.,Waring, M.J.,Noble, M.E.M.,Endicott, J.A.,Tatum, N.J. (deposition date: 2024-03-26, release date: 2025-04-09)
Primary citationHope, I.,Martin, M.P.,Waring, M.J.,Noble, M.E.M.,Endicott, J.A.,Tatum, N.J.
Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.38 Å)
Structure validation

236620

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