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9ESS

CDK2-cyclin A in complex with FragLite 22

Summary for 9ESS
Entry DOI10.2210/pdb9ess/pdb
DescriptorCyclin-dependent kinase 2, Cyclin-A2, (4-bromo-2-methoxyphenyl)methanol, ... (4 entities in total)
Functional Keywordscyclin-dependent kinase, fraglite, cdk2, cyclin a, fragment, cell cycle
Biological sourceHomo sapiens (human)
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Total number of polymer chains4
Total formula weight132298.03
Authors
Hope, I.,Martin, M.P.,Waring, M.J.,Noble, M.E.M.,Endicott, J.A.,Tatum, N.J. (deposition date: 2024-03-26, release date: 2025-04-09)
Primary citationHope, I.,Martin, M.P.,Waring, M.J.,Noble, M.E.M.,Endicott, J.A.,Tatum, N.J.
Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.44 Å)
Structure validation

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