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9ESQ

CDK2-cyclin A in complex with FragLite 24

Summary for 9ESQ
Entry DOI10.2210/pdb9esq/pdb
DescriptorCyclin-dependent kinase 2, Cyclin-A2, 4-bromanyl-2-oxidanyl-benzoic acid, ... (4 entities in total)
Functional Keywordscyclin-dependent kinase, fraglite, cdk2, cyclin a, fragment, cell cycle
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight132514.66
Authors
Hope, I.,Martin, M.P.,Waring, M.J.,Noble, M.E.M.,Endicott, J.A.,Tatum, N.J. (deposition date: 2024-03-26, release date: 2025-04-09)
Primary citationHope, I.,Martin, M.P.,Waring, M.J.,Noble, M.E.M.,Endicott, J.A.,Tatum, N.J.
Crystallographic fragment screening of CDK2-cyclin A: FragLites map sites of protein-protein interaction
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.38 Å)
Structure validation

237423

PDB entries from 2025-06-11

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