9EQH
WWP2 WW2-2,3-linker-HECT (WWP2-LH)
Summary for 9EQH
Entry DOI | 10.2210/pdb9eqh/pdb |
Descriptor | Isoform 2 of NEDD4-like E3 ubiquitin-protein ligase WWP2, GLYCEROL, SODIUM ION, ... (4 entities in total) |
Functional Keywords | ubiquitin, ligase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 53648.72 |
Authors | Dudey, A.P.,Hemmings, A.M. (deposition date: 2024-03-21, release date: 2024-05-15, Last modification date: 2024-09-18) |
Primary citation | Dudey, A.P.,Rigby, J.M.,Hughes, G.R.,Stephenson, G.R.,Storr, T.E.,Chantry, A.,Hemmings, A.M. Expanding the inhibitor space of the WWP1 and WWP2 HECT E3 ligases. J Enzyme Inhib Med Chem, 39:2394895-2394895, 2024 Cited by PubMed: 39223706DOI: 10.1080/14756366.2024.2394895 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.05 Å) |
Structure validation
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