9EP0

Dolichyl phosphate mannose synthase in complex with donor (GDP-Man) and traces of acceptor (Dol55P) and product (Dol55P-Man)

Summary for 9EP0

• Entry DOI: 10.2210/pdb9ep0/pdb
• Descriptor: Dolichol monophosphate mannose synthase, GUANOSINE-5'-DIPHOSPHATE-ALPHA-D-MANNOSE, MAGNESIUM ION, ... (5 entities in total)
• Functional Keywords: dolichyl phosphate mannose synthase, enzyme, integral membrane protein, protein glycosylation, glycosylphosphatidylinositol synthesis, gdp-mannose, dolichyl monophosphate, dolichol monophosphate mannose, donor-acceptor and product complex, transferase
• Biological source: Pyrococcus furiosus DSM 3638
• Total number of polymer chains: 1
• Total formula weight: 44451.94

Authors

Gandini, R.,Keskitalo, M.M.,Reichenbach, T.,Divne, C. (deposition date: 2024-03-16, release date: 2025-10-01)

• Primary citation: Gandini, R.,Keskitalo, M.,Reichenbach, T.,Divne, C.; Crystal structure of Pyrococcus furiosus dolichylphosphate mannose synthase in complex with substrates (GDP-Man and DolP) and traces of a flipped glycolipid product (DolP-Man); To be published,

Experimental method

X-RAY DIFFRACTION (2.9 Å)