9EOY
Structure of Thr354Asn, Glu355Gln, Thr412Asn, Ile414Met, Ile464His, and Phe467Met mutant human CaMKII alpha hub bound to PIPA
This is a non-PDB format compatible entry.
Summary for 9EOY
Entry DOI | 10.2210/pdb9eoy/pdb |
Descriptor | Calcium/calmodulin-dependent protein kinase type II subunit alpha, ACETATE ION, 2-[6-(4-chlorophenyl)imidazo[1,2-b]pyridazin-2-yl]ethanoic acid, ... (5 entities in total) |
Functional Keywords | camkii hub, oligomer, signaling protein |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 7 |
Total formula weight | 109984.94 |
Authors | Narayanan, D.,Larsen, A.S.G.,Solbak, S.M.O.,Wellendorph, P.,Gee, C.L.,Kastrup, J.S. (deposition date: 2024-03-15, release date: 2024-09-25) |
Primary citation | Narayanan, D.,Larsen, A.S.G.,Gauger, S.J.,Adafia, R.,Hammershoi, R.B.,Hamborg, L.,Bruus-Jensen, J.,Griem-Krey, N.,Gee, C.L.,Frolund, B.,Stratton, M.M.,Kuriyan, J.,Kastrup, J.S.,Langkilde, A.E.,Wellendorph, P.,Solbak, S.M.O. Ligand-induced CaMKII alpha hub Trp403 flip, hub domain stacking, and modulation of kinase activity. Protein Sci., 33:e5152-e5152, 2024 Cited by PubMed: 39275999DOI: 10.1002/pro.5152 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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