9EOH

PHF type tau filament from in vitro V337M mutant

Summary for 9EOH

Entry DOI	10.2210/pdb9eoh/pdb
Related	9EO7
EMDB information	19855
Descriptor	Isoform Tau-F of Microtubule-associated protein tau (1 entity in total)
Functional Keywords	phf, tau filament, v337m, protein fibril
Biological source	Homo sapiens (human)
Total number of polymer chains	6
Total formula weight	275711.63
Authors	Qi, C.,Lovestam, S.,Scheres, S.H.W.,Michel, G. (deposition date: 2024-03-14, release date: 2024-05-29)
Primary citation	Qi, C.,Lovestam, S.,Murzin, A.G.,Peak-Chew, S.,Franco, C.,Bogdani, M.,Latimer, C.,Murrell, J.R.,Cullinane, P.W.,Jaunmuktane, Z.,Bird, T.D.,Ghetti, B.,Scheres, S.H.W.,Goedert, M. Tau filaments with the Alzheimer fold in cases with MAPT mutations V337M and R406W. Biorxiv, 2024 Cited by PubMed: 38746388 DOI: 10.1101/2024.04.29.591661 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.8 Å)

Structure validation