9ENB

Human pseudouridine synthase 3 (PUS3 R116A mutant) and two tRNA-Gln

Summary for 9ENB

Entry DOI	10.2210/pdb9enb/pdb
EMDB information	16917 16926 19830
Descriptor	tRNA pseudouridine(38/39) synthase, tRNA-Gln, MAGNESIUM ION (3 entities in total)
Functional Keywords	rna modification, pseudouridylation, trna, homodimer, rna binding protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	159518.51
Authors	Lin, T.-Y.,Jezowski, J.,Glatt, S. (deposition date: 2024-03-12, release date: 2024-07-10, Last modification date: 2024-07-24)
Primary citation	Lin, T.Y.,Kleemann, L.,Jezowski, J.,Dobosz, D.,Rawski, M.,Indyka, P.,Wazny, G.,Mehta, R.,Chramiec-Glabik, A.,Koziej, L.,Ranff, T.,Fufezan, C.,Wawro, M.,Kochan, J.,Bereta, J.,Leidel, S.A.,Glatt, S. The molecular basis of tRNA selectivity by human pseudouridine synthase 3. Mol.Cell, 84:2472-2489.e8, 2024 Cited by PubMed: 38996458 DOI: 10.1016/j.molcel.2024.06.013 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (2.66 Å)

Structure validation