9EGI

Crystal Structure of EgtUC binding domain mutant T274G bound to L-Ergothioneine from S. pneumoniae

Summary for 9EGI

• Entry DOI: 10.2210/pdb9egi/pdb
• Descriptor: Ergothioneine transporter EgtUC, trimethyl-[(2S)-1-oxidanyl-1-oxidanylidene-3-(2-sulfanylidene-1,3-dihydroimidazol-4-yl)propan-2-yl]azanium (3 entities in total)
• Functional Keywords: l-ergothioneine, abc transporter, s. pneumoniae, transport protein
• Biological source: Streptococcus pneumoniae D39
• Total number of polymer chains: 2
• Total formula weight: 62509.22

Authors

Legg, K.A.,Gonzalez-Gutierrez, G.,Giedroc, D.P. (deposition date: 2024-11-21, release date: 2025-11-26)

• Primary citation: Legg, K.A.,Gonzalez-Gutierrez, G.,Edmonds, K.A.,Shushkov, P.G.,Giedroc, D.P.; C-H...S hydrogen bonds are essential for molecular recognition of ergothioneine by the bacterial ergothioneine transporter EgtUC in Streptococcus pneumoniae.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.95 Å)