9ECG

PANK3 complex structure with compound PZ-5588

This is a non-PDB format compatible entry.

Summary for 9ECG

• Entry DOI: 10.2210/pdb9ecg/pdb
• Descriptor: Pantothenate kinase 3, 1,2-ETHANEDIOL, N-(4-{2-[4-(6-chloropyridazin-3-yl)piperazin-1-yl]-2-oxoethyl}-2-fluorophenyl)ethanesulfonamide, ... (7 entities in total)
• Functional Keywords: pank, substrate, complex, transferase, pantothenate kinase, inhibitor, activator
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 43257.75

Authors

Yun, M.,Lee, R.E. (deposition date: 2024-11-14, release date: 2025-11-19)

• Primary citation: Tangallapally, R.,Coker, A.,Edwards, A.,Subramanian, C.,Jayasinghe, T.,Yun, M.,Jackowski, S.,Rock, C.O.,White, S.W.,Lee, R.E.; Isoform Selectivity Driven Pantothenate Kinases Activation by Novel Sulfonamide Analogues of Pantazines; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.092 Å)